Uncovering the Moral Heuristics of Altruism: A Philosophical Scale

Extant research suggests that individuals employ traditional moral heuristics to support their observed altruistic behavior; yet findings have largely been limited to inductive extrapolation and rely on relatively few traditional frames in so doing, namely, deontology in organizational behavior and virtue theory in law and economics. Given that these and competing moral frames such as utilitarianism can manifest as identical behavior, we develop a moral framing instrument—the Philosophical Moral-Framing Measure (PMFM)—to expand and distinguish traditional frames associated and disassociated with observed altruistic behavior. The validation of our instrument based on 1015 subjects in 3 separate real stakes scenarios indicates that heuristic forms of deontology, virtue-theory, and utilitarianism are strongly related to such behavior, and that egoism is an inhibitor. It also suggests that deontic and virtue-theoretical frames may be commonly perceived as intertwined and opens the door for new research on self-abnegation, namely, a perceived moral obligation toward suffering and self-denial. These findings hold the potential to inform ongoing conversations regarding organizational citizenship and moral crowding out, namely, how financial incentives can undermine altruistic behavior

Food for Thought: Genetically Modified Seeds as De Facto Standard Essential Patents

For several years, courts have been improperly calculating damages in cases involving the unlicensed use of genetically-modified (GM) seed technology. In particular, when courts determine patent damages based on the hypothetical negotiation method, they err in exaggerating these damages to a point where no rational negotiator would agree. In response, we propose a limited affirmative defense of an implied license due to the patent’s status as a de facto standard essential patent. To be classified as a de facto standard essential patent, the farmer must prove three elements that reflect the peculiarities of GM seeds used in farming: (1) dominance, (2) impracticability, and (3) necessary to fulfill a basic need. Based on the approaches used by courts and standard setting organizations in licensing standard essential patents in technological fields such as cell phones and software, designation of some GM seeds as standard essential patents allows the courts to imply a license from patentees to farmers on reasonable and non-discriminatory (RAND) terms. Doing so shifts the case from a tort-based patent infringement suit to a breach of contract dispute and alters the damages regime from one based in compensation, deterrence, and punishment (a tort approach) to one based solely in compensation (a contractual approach). As a result of this novel proposal, the damages calculations in these suits return to economic reality

Hyperbaric Oxygen Therapy Alters Vascular Reactivity Independent of Elevations in ATP

Hyperbaric oxygen (HBO) is a pharmacologic therapy used treat a variety of medical conditions. The underlying mechanisms of HBOs effect on vascular reactivity are poorly understood. The purpose of this study was to record the acute effects of HBO on vascular reactivity and determine the potential role of ATP in mediating these effects. Porcine mesenteric arteries were dissected and mounted in isolated organ baths to record changes in tension in response to potassium chloride (KCl, 15-60 mM), phenylephrine (PHE, 10-7-10-4 M), and sodium nitroprusside (SNP, 10-7-10-4 M) following a 2-hour exposure to HBO (1.75 ATA). HBO augmented responses to KCl and PHE compared to control arteries exposed to room air or nitrogen at 1.75 ATA as well as to room air at 1 atm. When compared to the 1 ATA room air control, KCl-induced constriction was significantly increased for the HBO exposure. Treatment with HBO also augmented vascular responses to PHE and SNP relative to nitrogen, but not ambient air. We hypothesized that HBO increased ATP production in vascular smooth muscle leading to enhanced vascular reactivity. Consequently, ATP levels were measured in mesenteric arteries but no significant differences in ATP levels were observed regardless of hyperbaric treatment. Direct measurements of ATPs’ effects on porcine vasculature with and without hyperbaric treatment resulted in no significant findings. These results suggest that HBO alters vascular reactivity independent of elevations in ATP

The Sunyaev Zel'dovich effect: simulation and observation

The Sunyaev Zel'dovich effect (SZ effect) is a complete probe of ionized baryons, the majority of which are likely hiding in the intergalactic medium. We ran a $512^3$ $\Lambda$CDM simulation using a moving mesh hydro code to compute the statistics of the thermal and kinetic SZ effect such as the power spectra and measures of non-Gaussianity. The thermal SZ power spectrum has a very broad peak at multipole $l\sim 2000-10^4$ with temperature fluctuations $\Delta T \sim 15\mu$K. The power spectrum is consistent with available observations and suggests a high $\sigma_8\simeq 1.0$ and a possible role of non-gravitational heating. The non-Gaussianity is significant and increases the cosmic variance of the power spectrum by a factor of $\sim 5$ for $l<6000$. We explore optimal driftscan survey strategies for the AMIBA CMB interferometer and their dependence on cosmology. For SZ power spectrum estimation, we find that the optimal sky coverage for a 1000 hours of integration time is several hundred square degrees. One achieves an accuracy better than 40% in the SZ measurement of power spectrum and an accuracy better than 20% in the cross correlation with Sloan galaxies for $2000<l<5000$. For cluster searches, the optimal scan rate is around 280 hours per square degree with a cluster detection rate 1 every 7 hours, allowing for a false positive rate of 20% and better than 30% accuracy in the cluster SZ distribution function measurement.Comment: 34 pages, 20 figures. Submitted to ApJ. Simulation maps have been replaced by high resolution images. For higher resolution color images, please download from http://www.cita.utoronto.ca/~zhangpj/research/SZ/ We corrected a bug in our analysis. the SZ power spectrum decreases 50% and y parameter decrease 25

What Extension Personnel Should Know About Midwestern Goat Producers

The growth of the goat industry has created opportunities for producers looking for a profitable alternative enterprise. Little is known about goat production or educational needs of producers in Missouri and Arkansas. A survey of goat producers in Missouri and Arkansas addressed farm characteristics, product marketing characteristics, preferred information sources, and educational topics of interest for goat producers. A better understanding of goat production and producer needs can support Extension\u27s development of education programs to further develop the emerging goat industry

Subset of Heat-Shock Transcription Factors Required for the Early Response of Arabidopsis to Excess Light

Sunlight provides energy for photosynthesis and is essential for nearly all life on earth. However, too much or too little light or rapidly fluctuating light conditions cause stress to plants. Rapid changes in the amount of light are perceived as a change in the reduced/oxidized (redox) state of photosynthetic electron transport components in chloroplasts. However, how this generates a signal that is relayed to changes in nuclear gene expression is not well understood. We modified redox state in the reference plant, Arabidopsis thaliana, using either excess light or low light plus the herbicide DBMIB (2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone), a well-known inhibitor of photosynthetic electron transport. Modification of redox state caused a change in expression of a common set of about 750 genes, many of which are known stress-responsive genes. Among the most highly enriched promoter elements in the induced gene set were heat-shock elements (HSEs), known motifs that change gene expression in response to high temperature in many systems. We show that HSEs from the promoter of the ASCORBATE PEROXIDASE 2 (APX2) gene were necessary and sufficient for APX2 expression in conditions of excess light, or under low light plus the herbicide. We tested APX2 expression phenotypes in overexpression and loss-of-function mutants of 15 Arabidopsis A-type heat-shock transcription factors (HSFs), and identified HSFA1D, HSFA2, and HSFA3 as key factors regulating APX2 expression in diverse stress conditions. Excess light regulates both the subcellular location of HSFA1D and its biochemical properties, making it a key early component of the excess light stress network of plants

The Periodic Standing-Wave Approximation: Overview and Three Dimensional Scalar Models

The periodic standing-wave method for binary inspiral computes the exact numerical solution for periodic binary motion with standing gravitational waves, and uses it as an approximation to slow binary inspiral with outgoing waves. Important features of this method presented here are: (i) the mathematical nature of the ``mixed'' partial differential equations to be solved, (ii) the meaning of standing waves in the method, (iii) computational difficulties, and (iv) the ``effective linearity'' that ultimately justifies the approximation. The method is applied to three dimensional nonlinear scalar model problems, and the numerical results are used to demonstrate extraction of the outgoing solution from the standing-wave solution, and the role of effective linearity.Comment: 13 pages RevTeX, 5 figures. New version. A revised form of the nonlinearity produces better result

Feedforward control of thermal history in laser powder bed fusion: Toward physics-based optimization of processing parameters

We developed and applied a model-driven feedforward control approach to mitigate thermal-induced flaw formation in laser powder bed fusion (LPBF) additive manufacturing process. The key idea was to avert heat buildup in a LPBF part before it is printed by adapting process parameters layer-by-layer based on insights from a physics-based thermal simulation model. The motivation being to replace cumbersome empirical build-and-test parameter optimization with a physics-guided strategy. The approach consisted of three steps: prediction, analysis, and correction. First, the temperature distribution of a part was predicted rapidly using a graph theory-based computational thermal model. Second, the model-derived thermal trends were analyzed to isolate layers of potential heat buildup. Third, heat buildup in affected layers was corrected before printing by adjusting process parameters optimized through iterative simulations. The effectiveness of the approach was demonstrated experimentally on two separate build plates. In the first build plate, termed fixed processing, ten different nickel alloy 718 parts were produced under constant processing conditions. On a second identical build plate, called controlled processing, the laser power and dwell time for each part was adjusted before printing based on thermal simulations to avoid heat buildup. To validate the thermal model predictions, the surface temperature of each part was tracked with a calibrated infrared thermal camera. Post-process the parts were examined with non-destructive and destructive materials characterization techniques. Compared to fixed processing, parts produced under controlled processing showed superior geometric accuracy and resolution, finer grain size, increased microhardness, and reduced surface roughness

Addressing the Accessibility of Social Media

Social media platforms are deeply ingrained in society, and they offer many different spaces for people to engage with others. Unfortunately, accessibility barriers prevent people with disabilities from fully participating in these spaces. Social media users commonly post inaccessible media, including videos without captions (which are important for people who are deaf or hard of hearing) and images without alternative text (descriptions read aloud by screen readers for people who are blind). Users with motor impairments must find workarounds to deal with the complex user interfaces of these platforms, and users with cognitive disabilities may face barriers to composing and sharing information. Accessibility researchers, industry practitioners, and end-users with disabilities will come together to outline challenges and solutions for improving social media accessibility. The workshop starts with a panel of end-users with disabilities who will recount their Perspectives of Successes and Barriers. Industry professionals from social media companies (e.g., Facebook and LinkedIn) will detail their Design Process and Implementation Challenges in a panel with questions from attendees. The attendees will share their work and tackle Open Challenges and Future Research Directions. This workshop will forge collaborations between researchers and practitioners, and define high-priority accessibility challenges for social media platforms

Kinematic Distances to Molecular Clouds identified in the Galactic Ring Survey

Kinematic distances to 750 molecular clouds identified in the 13CO J=1-0 Boston University-Five College Radio Astronomy Observatory Galactic Ring Survey (BU-FCRAO GRS) are derived assuming the Clemens rotation curve of the Galaxy. The kinematic distance ambiguity is resolved by examining the presence of HI self-absorption toward the 13CO emission peak of each cloud using the Very Large Array Galactic Plane Survey (VGPS). We also identify 21 cm continuum sources embedded in the GRS clouds in order to use absorption features in the HI 21 cm continuum to distinguish between near and far kinematic distances. The Galactic distribution of GRS clouds is consistent with a four-arm model of the Milky Way. The locations of the Scutum-Crux and Perseus arms traced by GRS clouds match star count data from the Galactic Legacy Infrared Mid-Plane Survey Extraordinaire (GLIMPSE) star-count data. We conclude that molecular clouds must form in spiral arms and be short-lived (lifetimes < 10 Myr) in order to explain the absence of massive, 13CO bright molecular clouds in the inter-arm space